Biologically, it nails a genuine truth: many organs slow down at night while the kidneys keep working tirelessly. Even when you’re asleep, they’re filtering blood, regulating fluids, and making urine. It’s a quiet, ceaseless process — almost like the body’s unsung night-shift worker.

Philosophically, the strip hints at something deeper: how some responsibilities never pause, even when everything else seems at rest. It mirrors people who quietly bear burdens or maintain order behind the scenes, often without recognition. There’s a touch of existential comedy in the idea that “rest” is selective — and that effort, dedication, or even worry doesn’t always clock out.